How Agile working can solve tough challenges

Tuberculosis is still a rampant problem in the developing world. Doctors are looking for even more advanced ways to test for TB beyond the GeneXpert tests.

Twelve million people are blind in India, and are robbed of their livelihoods as a result. A hugely successful chain of cataract hospitals in India helped its business by treating half its patients for free.

One-pill-a-day generic AIDS drugs for poor countries are hard to make because each ingredient is patented by a different pharmaceutical company. The Patent Pool provides a way for companies to donate their intellectual property safely.

The pressure is on for the federal government to spend tax money more wisely. Evidence-based policy making is gaining in popularity as a way for the government to spend tax money wisely. While not quite as flashy or exciting as past ways, this has a proven track record of positive impact.

Amidst a world struggling with smart ways to confront climate change, Hawaii's 2050 Plan for sustainability is working to be a model for the rest of the world. So far, it is on it's way to being a leader in solar energy, with Honolulu having the most "solar panels per capita than any other North American city," and the state is working to produce more food locally, as well.

Colombia has attempted to decrease murder and homicide rates by setting up curfews for teenagers, forcing bars to close earlier in the evening, and creating gun laws to prevent the carrying of weapons. As a result of this epidemiological, data-driven approach, along with other governmental factors, the homicide rate has decreased significantly in most of the cities in which it was implemented.

Most insurance companies avoid insuring poor farmers because the transaction costs are too high, but a non-profit in Kenya created a sustainable way to cover them.

As Vermont struggles to create legislation regulating school district management and financial efficiency, the state looks to models in Maine and New Hampshire for guidance. In Maine, school districts have tried to save money and resources through consolidation; in New Hampshire, officials have reworked the way schooling is financed altogether.

Colorado causes a large decline in teen pregnancy and abortions by implementing free, long-term birth control to prevent pregnancy. While demonstrating massive success, its continuity is in the air considering the ongoing fight over health insurance at the federal level.

The California prison system is overwhelmed after adopting tough-on-crime laws with no improvement. New York adopted more tolerant policies and has decreased the state's crime rate and its prison population.